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Elicio Therapeutics

NASDAQ: ELTX $3.85 USD ~$80M (post-Phase 2 miss, June 2026) MCAP

Elicio Therapeutics is a clinical-stage biotechnology company developing potent immunotherapies using its proprietary Amphiphile vaccine platform, which delivers immunogens directly to the lymph nodes to amplify immune responses against cancer. Its lead program ELI-002 is a KRAS-targeted cancer vaccine being studied in mKRAS-positive pancreatic ductal adenocarcinoma and other solid tumors. In June 2026 the Phase 2 AMPLIFY-201 trial missed its primary endpoint, sending shares down sharply, though the company said it will still advance to a Phase 3 study based on a subpopulation signal.

Company Info

Sector: Biotechnology / Oncology (Cancer Vaccines)
Headquarters: Cambridge, Massachusetts, USA
Founded: 2011
Website: elicio.com/

Upcoming Milestones & Key Dates

Q3 2026
Clinical Trial

Detailed AMPLIFY-201 Phase 2 subpopulation analysis and Phase 3 design

H2 2026
Corporate

Investor update on strategic pipeline priorities and cash runway

Clinical Development Pipeline

ELI-002 (7P)

Target: Amphiphile lymph-node-targeted KRAS peptide vaccine
KRAS G12D-mutant pancreatic ductal adenocarcinoma (adjuvant)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

ELI-002 2P

Target: Amphiphile lymph-node-targeted KRAS peptide vaccine
KRAS G12D / G12V-mutant solid tumors
Preclinical
Phase 1
Phase 2
Phase 3
Approved

ELI-004

Target: Amphiphile vaccine platform, B-cell lymphoma
B-cell malignancies (undisclosed targets)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Recent News

Therapeutics Development Endpoints News

Elicio's KRAS Cancer Vaccine Fails in Phase 2, Shares Plummet

Elicio Therapeutics' KRAS-targeted cancer vaccine failed to meet its primary Phase 2 endpoint in metastatic pancreatic cancer, sending shares down more than 60% and forcing a strategic review of the platform.

Leadership Team

Robert Connelly

Chief Executive Officer

To be confirmed

Chief Medical Officer

Dr. Eric K. Rowinsky

Acting Chief Medical Officer

Careers & Job Openings

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Multiple Departments
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