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Structure Therapeutics

Nasdaq: GPCR $44.51 USD ~$1.5B (post-ADA Phase 2 readout) MCAP

Structure Therapeutics is a clinical-stage biopharmaceutical company developing oral small-molecule therapies for serious diseases, with a lead program (GSBR-1290) in oral GLP-1 receptor agonism for obesity and type 2 diabetes. The company's pipeline targets GPCR-driven metabolic and cardiopulmonary diseases, leveraging structure-based drug design to create differentiated oral alternatives to injectable peptide therapies.

Company Info

Sector: Biotechnology / Small-Molecule Metabolic Disease
Headquarters: South San Francisco, California, USA
Founded: 2017

Upcoming Milestones & Key Dates

H2 2026
Regulatory

End-of-Phase 2 meeting with FDA on GSBR-1290 obesity program

Late 2026 / 2027
Clinical Trial

GSBR-1290 Phase 3 initiation in obesity

Clinical Development Pipeline

GSBR-1290

Target: Oral small-molecule GLP-1 receptor agonist
Obesity and type 2 diabetes
Preclinical
Phase 1
Phase 2
Phase 3
Approved

ANPA-0073

Target: Apelin receptor agonist
Pulmonary arterial hypertension (PAH)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

LTSE-2578

Target: Lysophosphatidic acid receptor 1 (LPA1) antagonist
Idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Recent News

Leadership Team

To be confirmed

Chief Executive Officer

To be confirmed

Chief Medical Officer

To be confirmed

Chief Scientific Officer

Careers & Job Openings

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Multiple Departments
See careers page
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