Companies in #Neurodegeneration
Found 6 companies operating in this sector.
Alector is a clinical-stage biotechnology company developing immuno-neurology therapies for neurodegenerative diseases. Its lead programs target progranulin (PGRN) and TREM2 pathways, with a major 2026 setback when partner GSK walked away from its $700M upfront Alzheimer's collaboration after consecutive clinical failures.
BioVie Inc. (NASDAQ: BIVI) is a clinical-stage company developing innovative drug therapies for the treatment of neurological and neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and long COVID, as well as advanced liver disease.
Denali Therapeutics (NASDAQ: DNLI) is a biotechnology company headquartered in South San Francisco, California, developing a broad portfolio of therapeutics for neurodegenerative diseases through its proprietary blood-brain barrier (BBB) delivery platform (the ATV/Otv platform, including Enzyme Transport Vehicle and Oligonucleotide Transport Vehicle technologies). Denali's clinical and preclinical pipeline targets Parkinson's disease (BIIB122/DNL151, partnered with Biogen), Hunter syndrome (DNL310, tividenofusp alfa), ALS (DNL343), and multiple other lysosomal storage diseases and neurodegenerative indications. The company was founded in 2015 by a team that included former Genentech scientists.
Jupiter Neurosciences is a clinical-stage pharmaceutical company developing treatments for central nervous system (CNS) disorders, with a focus on psychedelic-assisted therapy and neurodegenerative diseases. The company is advancing JNS-101 (MDMA analog) and other CNS-targeting candidates.
Skyhawk Therapeutics
PrivateSkyhawk Therapeutics is a clinical-stage biotechnology company developing small-molecule RNA splicing modulators using its proprietary SkySTAR platform, with programs in neurology, oncology, autoimmune, and fibrotic diseases.
Tempus AI is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. Its platform collects and analyzes clinical and molecular data to enable physicians and researchers to make data-driven decisions in oncology, cardiology, and other disease areas.